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Articles Pharma Industry

03.2011
Somnath S. Kadam , Herman J.M. Kramer , and Joop H. ter Horst The combination of a single primary nucleation event and secondary nucleation in crystallization processes. Cryst. Growth Des., Article

01.2011
Jiang S. and ter Horst J.H. (2010) Crystal Nucleation Rates from Probability Distributions of Induction Times, Cryst. Growth Des., 11 (1), 256-261. Abstract

09.2010
Fetha M.P., Nagelb N., Baumgartnerb B., Bröckelmannb M., Rigala D., Ottoa B., Spitzenberga M., Schulza M, Beckera B., Fischera F. and Petzoldt C. (2010) Challenges in the development of hydrate phases as active pharmaceutical ingredients - An example, European Journal of Pharmaceutical Sciences, 42 (1-2), 116-129. Abstract

08.2010
Srisanga S. and ter Horst J.H. (2010) Racemic Compound, Conglomerate, or Solid Solution: Phase Diagram Screening of Chiral Compounds, Cryst. Growth Des., 10 (4), 1808-1812. Abstract

07.2010
Habgood M., Deij, M.A., Mazurek J., Price S.L. and ter Horst J.H. (2010) Carbamazepine Co-crystallization with Pyridine Carboxamides: Rationalization by Complementary Phase Diagrams and Crystal Energy Landscapes, Cryst. Growth Des., 10 (2), 903-912. Abstract

06.2010
Tulashie S.K., von Langermann J., Lorenz H. and Seidel-Morgenstern A. (2010) Chiral Task-Specific Solvents for Mandelic Acid and Their Impact on Solution Thermodynamics and Crystallization Kinetics, Cryst. Growth Des. Abstract

05.2010
Kadam S.S., van der Windt E, Daudey P.J. and Kramer H.J.M. (2010) A Comparative Study of ATR-FTIR and FT-NIR Spectroscopy for In-Situ Concentration Monitoring during Batch Cooling Crystallization Processes, Cryst. Growth Des., 10 (6), 2629-2640. Abstract

04.2010
Billot P., Couty M. and Hosek P. (2010) Application of ATR-UV Spectroscopy for Monitoring the Crystallisation of UV Absorbing and Nonabsorbing Molecules, Org. Process Res. Dev., 14 (3), 511-523. Abstract

03.2010
Sistla A,Wu Y, Khamphavong P and Liu J (2010) Medium-throughput hydrate screening using the Crystal 16(TM)., Pharmaceutical development and technology, 1- 8. Abstract

02.2010
Sistla V. S., von Langermann J., Lorenz H. and Seidel-Morgenstern A. (2010) Application of Classical Resolution for Separation of DL-Serine, Chemical Engineering & Technology, 33, 780-786. Abstract

01.2010
Boyd S., Back K.,Chadwick K.,Davey R.J. and Seaton C.C. (2010) Solubility, metastable zone width measurement and crystal growth of the 1:1 benzoic acid/isonicotinamide cocrystal in solutions of variable stoichiometry, Journal of Pharmaceutical Sciences, 99, 3779-3786. Abstract

05.2009
Dickens J., Swinney K. and Stockbroekx S. (2009) Crystallization: The Broad Perspective, American Pharmaceutical Review. Click here to request a paper copy

04.2009
Howard K.S., Nagy Z.K., Saha B., Robertson A.L., Steele G. and Martin D. (2009) A Process Analytical Technology Based Investigation of the Polymorphic Transformations during the Antisolvent Crystallization of Sodium Benzoate from IPA/Water Mixture, Cryst. Growth Des., 9 (9), 3964-3975. Abstract

03.2009
Argentine M.D., Braden T.M., Czarnik J., Conder E.W., Dunlap S.E., Fennell J.W., LaPack M.A., Rothhaar R.R., Scherer R.B., Schmid C.R., Vicenzi J.T., Wei J.G. and Werner J (2009) The Role of New Technologies in Defining a Manufacturing Process for PPAR? Agonist LY518674, Org. Process Res. Dev., 13 (2), 131-143.

02.2009
Howard K. S.,Nagy Z.K., Saha B,Robertson A.L. and Steele G (2009) Combined PAT-Solid State Analytical Approach for the Detection and Study of Sodium Benzoate Hydrate, Org. Process Res. Dev., 13 (3), 590-597. Abstract

01.2009
ter Horst J.H.,Deij M.A. and Cains P.W. (2009) Discovering New Co-Crystals, Cryst. Growth Des., 9 (3), 1531-1537. Abstract

01.2008
ter Horst J.H. and Cains P.W. (2008) Co-Crystal Polymorphs from a Solvent-Mediated Transformation, Cryst. Growth Des., 8 (7), 2537-2542. Abstract

02.2007
ter Horst J.H., Cains P.W. and van Rosmalen G.M. (2007) Co-crystallization of Carbamazepine and Isonicotinamide: Two New Co-crystal Forms?, BIWIC 2007, 143-152. Article

01.2007
Kumara L., Amina A. and Bansal A.K. (2007) An overview of automated systems relevant in pharmaceutical salt screening, Drug Discovery Today, 12 (23-24), 1046-1053. Abstract

01.2007
Solid-state Chemistry in Drug Development

01.2006
Smith A.A.,McKay B., Damen E.W.P., Darphorn-Hooijschuur S.,Ras E., and Verspui G. (2006) Prediction of Maximum Yield in the Crystallization of Multicomponent Isomeric Systems, Org. Process Res. Dev., 10 (6), 1132-1143. Article

01.2005
Birch M., Fussell S.J., Higginson P.D.,McDowall N. and Marziano I. (2005) Towards a PAT-Based Strategy for Crystallization Development, Org. Process Res. Dev., 9 (3), 360-364. Abstract

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